XCeloSeq Colon Cancer FFPE Kit
®
NGS Library Preparation kit for use with FFPE DNA for detecting common colon cancer mutations
Using ATOM-Seq, capture single- and double-strand DNA from your FFPE DNA sample for use with even the poorest quality samples. Incorporating both UMIs and enzymatic removal of C>U deamination artifacts ensures the high quality results for the detection of mutation in genes used in therapy guidance on colon cancer and for the detection of lynch syndrome.
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Due for release in 2025.
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Product Details
Specifications
%Targeting primers are split between pool 1 which enriches sense DNA and pool 2 which enriches antisense DNA.
*Higher quantities will improve maximum sensitivity.
Target Genes
Targets mutation hotspots across 23 genes most frequently mutated in colon cancers
*Whole coding region coverage (NM_000546, NM_001126113, and NM_001126114)
DPYD variants rs67376798, DPYD*A2 (rs3918290), rs55886062 and HapB3 (rs75017182, rs56038477) are covered.
Please contact us to discuss customising this panel.
Read about all our customisation options here.
Benefits
Capture more of your patient sample with ATOM-Seq which captures all single stranded, double-stranded or nicked DNA of any length.
Detect even the rarest clinical signatures by using both UMIs and unique, error-reducing workflow optimisations
Simple, single-day protocols leveraging the inherent simplicity and efficiency of DNA polymerases
Unique Dual Indexes
Unique Dual Indexes (UDIs) are required to be purchased and are sold separately
Please contact us to discuss additional index options.
Resources
Please contact us for information and updates for release.
For Research Use Only (RUO).
Not for use in diagnostic procedures.
Not intended to be used for treatment of human or animal diseases.